摘要
目的研究文冠果Xanthoceras sorbifolia花的化学成分。方法采用制备薄层色谱、反复硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱等方法进行分离纯化,根据理化性质及光谱数据鉴定化合物的结构。结果从文冠果花的70%乙醇提取物中分离得到8个化合物,分别鉴定为文冠果酮A(1)、山柰酚-3-O-α-L-吡喃鼠李糖苷(2)、3-O-甲基槲皮素(3)、山柰酚-3-O-β-D-吡喃葡萄糖苷(4)、异槲皮苷(5)、杨梅素-3-O-芸香糖苷(6)、酪醇(7)、异东莨菪素(8)。结论化合物1为一新的单萜类化合物,并通过CD试验确定了绝对构型,化合物2～5、8为首次从文冠果属植物中分离得到。
Objective To study the chemical constituents in the flowers ofXanthoceras sorbifolia. Methods The constituents were isolated and purified by preparative TLC and silica gel, Sephadex LH-20, and ODS column chromatographies, and their structures were elucidated on the basis of their physicochemical properties and spectral data. Results Eight compounds were obtained and identified as xanthocerone A （1）, kaempferol-3-O-α-L-rhamnopyranoside （2）, 3-O-methyl-quercetin （3）, kaempferol-3-O-β-D-glucopyranoside （4）, isoquercitrin （5）, myricetin-3-O-rutinoside （6）, tyrosol （7）, and isoscopoletin （8）. Conclusion Compound 1 is a new monoterpenoid and its absolute configuration is determined by CD technique. Compounds 2-5 and 8 are isolated from the plants of Xanthoceras Bge. for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2013年第1期11-15,共5页
Chinese Traditional and Herbal Drugs
基金
辽宁省博士启动基金资助(20081037)
关键词
文冠果
单萜
文冠果酮A
3-O-甲基槲皮素
异东莨菪素
Xanthoceras sorbifolia Bunge
monoterpenoid
xanthocerone A
3-O-methyl-quercetin
isoscopoletin
