摘要
目的分析先天性心脏病(先心病)介入治疗的近期及远期疗效。方法入选512例行介入治疗的先心病患者,回顾性分析其术中及其术后的相关临床资料。结果本组介入手术总成功率为98.44%(504/512)。出现以下主要并发症:脑血栓栓塞1例(ASD封堵术)、封堵器脱落1例(ASD封堵术)、心包填塞2例(ASD封堵术1例,PS球囊成形术1例)、溶血1例(VSD封堵术)、Ⅲ度房室传导阻滞1例(VSD封堵术)、髂静脉损伤1例(PDA封堵术),主要并发症发生率为1.37%(7/512);死亡1例,病死率为0.20%(1/512)。随访6个月,ASD封堵术患者术后的左室舒张末径及左室射血分数较术前明显升高,右室内径较术前明显缩小(P<0.05);PDA封堵术患者术后左室舒张末径及收缩末径较术前明显缩小(P<0.05);VSD封堵术患者术后左室舒张末径较术前明显缩小(P<0.05);PS球囊成形术患者术后右室内径较术前明显缩小(P<0.05)。结论先心病介入治疗具有成功率高、并发症少、病死率低、疗效好等优点,能够显著改善心脏结构及功能。
Objective To analyze the short and long - term curative effects of interventional therapy on congenital heart disease. Methods 512 patients with congenital heart disease who received the interventional therapy were selected. Their clinical data during and after the operation were retrospectively analyzed. Results The overall successful rate of the interventional operation was 98.44% （504/512）. The major complications included cerebral thromboembolism in one case （receiving ASD）, the abscission of blockage in one case （ receiving ASD）, pericardial tampenade in 2 cases （ one receiving ASD and one doing balloon angioplasty）, hemolysis in one case（ receiving VSD）, atrioventricular block in III degree in one case（ receiving VSD）, and injury of iliac vein in one case（ receiving PDA）. The incidence of main complications was 1.37 % （7/512）. Death occurred in one case, and the mortality was 0. 20% （1/512）. In the 6 - month follow - up,the left ventricular end - diastolic diameter and left ventricular ejection fraction of patientsreceiving ASD were significantly higher than those parameters before the operation, while the right ven^cular diameter significantly decreased（ P 〈 0.05 ）. The left ventricular end ~ diastolic diameter and left ventricular end systolic diameter of patients receiving PDA significantly decreased after the operation （ P 〈 0. 05 ）. The left ventricular end - diastolic diameter of patients receiving VSD significantly decreased （ P 〈 0.05 ）. The right ventricular diameter of patients receiving PS balloon angioplasty surgery significantly decreased after the operation （ P 〈 0.05 ）. Conclusion The interventional therapy on congenital heart disease has advantages of a high successful rate, fewer complications, and lower mortality and can significantly improve the cardiac structure and function.
出处
《西南国防医药》
CAS
2013年第1期59-62,共4页
Medical Journal of National Defending Forces in Southwest China
关键词
先天性心脏病
介入治疗
疗效
congenital heart disease
interventional therapy
curative effect
