摘要
目的探讨胰十二指肠切除术后胰漏相关危险因素,为临床的防治提供参考。方法回顾性分析我院自2005年7月至2012年7月期间收治的121例患者行胰十二指肠切除术的临床资料,18例患者发生胰漏(实验组),未发生胰漏患者103例(对照组),两组进行单因素非条件和多因素非条件的Logistic回归分析。结果单因素分析结果显示胰管直径、胰管支撑引流例数、应用生长抑素例数、胰腺质地、胰头癌例数及术前胆红素(≥171μmol/L)与胰十二指肠切除术后胰漏的发生相关,差异有统计学意义(P<0.05);多因素非条件的Logistic回归分析显示术前胆红素(≥171μmol/L)、胰腺质地、胰头癌及胰管支撑引流例数与胰十二指肠切除术后胰漏相关(P<0.05)。结论术前胆红素(≥171μmol/L)、胰腺质地、胰头癌及胰管支撑引流例数是胰十二指肠切除术后胰漏的独立危险因素。
Objective To explore the related risk factors of 121 cases of pancreatic fistula after pancreaticoduodeneetomy.. Methods 121 pancreticoduedenectomy patients were retrospective analyzed from July 2005 to July 2012. There are 18 cases of patients with pancreatic leakage（group）, there are 103 patients（control group）, experimental group and the control group have performed single factor non-conditional and non-conditional logistic regression analysis. Results Single factor analysis results showed that pancreatic leakage after pancreaticoduodenectomy is closely related to ductal pancreatic duct drainage diameter, support, application growth inhibition change,pancreas, quality of thematerial, the head of pancreas cancer and preoperative bilirubin （≥ 171 umol/L）,the difference was statistically significant（P〈0.05） ;Many factors of Logistic regression showed that it is closely related to preoperative bilirubin（≥171 umol/L）, pancreas,quality of the material, the head of pancreas cancer and drainage of the pancreatic duct support（P〈0.05）. Conclusion Preoperative bilirubin（≥171 u mol/L）, pancreas,quality of a material, the head of pancreas cancer and drainage of the pancreatic duct support are risk factors for pancreatic leakage after pancreaticoduodenectomy.
出处
《成都医学院学报》
CAS
2012年第4期643-645,共3页
Journal of Chengdu Medical College
基金
中国高校医学期刊临床专项资金(NO:11221625)
关键词
胰十二指肠切除术
术后胰漏
危险因素
pancreaticoduodenectomy
Postoperative pancreatic leakage
Risk factors
