摘要
目的:探讨原发性胃恶性淋巴瘤(primary gastric malignant lymphoma,PGL)的临床特点、诊断与治疗及其预后。方法:回顾性分析4年半内收治的24例PGL患者的临床资料。结果:临床表现以上腹痛、消化道出血、纳差、消瘦多见。病变主要位于胃窦和胃体,术后病理类型均为非霍奇金淋巴瘤,其中B淋巴细胞型11例,T淋巴细胞型3例,BT双淋巴细胞型1例,未分型9例。ⅠE期9例(37.5%),ⅡE期7例(29.2%),ⅢE期6例(25.0%),ⅣE期2例(8.3%)。4例HP感染者术后给予抗HP治疗。在获得最终随访的21例中有13例存活超过5年。结论:PGL根据临床症状、内镜下特点及活检多能确诊。肿瘤病理类型、临床分期、是否存在合并症和HP感染是影响预后的重要因素。手术治疗有助于提高远期生存率,改善预后。
Objective：To investigate the clinical characteristics, diagnosis, treatment and prognostic of primary gastric malignant lymphoma. Methods： The clinical data of 24 patients with PGL treated in our hospital was analyzed retrospectively. Results： The main clinical manifestations were epigastric pain, gastrointestinal bleeding, poor appe- tite, emaciation. Endoscopically, ulceration, diffused infiltration, nodular could be observed. The lesions were located mainly in the antrum and body of stomach. All patients underwent surgical treatment, 19 cases with subtotal gastrecto- my（ B - Ⅰ/B - Ⅱ）, 5 cases total gastrectomy. All cases were diagnosed as non - Hodgking lymphoma pathologically, of them 11 were B lymphocyte,3 were T lymphocyte, 1 was BT lymphocyte ,9 were non classification. Ⅰ r stage 9 ca- ses （ 37.5 % ）, ⅡE stage 7 cases （29.2%）, Ⅲ E stage 6 cases （25.0%）, Ⅳ E stage 2 cases （ 8.3 % ）. 4 cases of HP infection treatment to anti - HP. The prognosis was correlated with histological type and clinical staging. 13 cases sur- vived more than 5 years. Conclusion： PGL can be confirmed according to clinical symptoms, endoscopic features, and biopsies. Histological type, clinical stage, the existence of complications and H. pylori infection are important factors affecting the prognosis. Surgical treatment can improve the long - term survival and improve prognosis.
出处
《现代肿瘤医学》
CAS
2013年第1期138-140,共3页
Journal of Modern Oncology
关键词
胃
淋巴瘤
原发性
诊断
治疗
gastric
lymphoma
primary
diagnosis
treatment
