摘要
目的探讨低蛋白血症对重度子痫前期妊娠结局的影响及其相关的处理和治疗。方法回顾性分析2009年1月～2012年6月笔者所在医院收治的247例重度子痫前期患者的临床资料,将所有患者分为两组,A组:低蛋白血症组134例,B组:非低蛋白血症组113例,比较两组患者的妊娠结局。结果 A组患者血压、蛋白尿均显著高于B组,且发病孕周早,严重并发症发生率高(P<0.05)。与B组相比,A组的新生儿体重较低,新生儿窒息、围生儿死亡率高(P<0.05)。结论重度子痫前期患者常合并低蛋白血症,易导致母亲及围生儿预后不良。血浆蛋白的变化具有非常重要的临床意义,应作为重度子痫前期常规监测指标。
Objective To explore the pregnancy outcomes and treatment of severe preeclampsia with hypoproteinemia. Methods We reviewed 247 patients with severe preeclampsia in our hospital during the period from January 2009 to June 2012. All patients were divided into two groups：group A （hypoproteinemia group of 134 cases）and group B（non-hypoproteinemia group of 113 cases）. The pregnancy outcomes of the two groups were compared. Results Patients in group A developed preeclampsia earlier than group B. The blood pressure,urine protein and the rate of serious complications of group A were obviously higher than group B（P 〈 0.05）. There were significant differences in birth weight,newborn asphyxia and perinatal mortality rate between group A and group B（P 〈 0.05）. Conclusion Severe preeclampsia usually complicated with hypoproteinemia,which is likely resulted in poor outcomes of both maternal and perinata babies. Plasma protein level posses a great clinical significance,and is suggested to be one of the routine monitoring indexes.
出处
《中国医药科学》
2013年第1期17-18,25,共3页
China Medicine And Pharmacy
基金
上海市浦东新区卫生局卫生科技面上项目(PW2010A-27)
关键词
重度子痫前期
低蛋白血症
妊娠结局
Severe preeclampsia
Hypoproteinemia
Pregnancy outcome
