摘要
目的探讨经皮肾镜取石术患者结石标本的细菌培养与膀胱中段尿培养之间的关系,以及与术后发生全身炎症反应的关系。方法收集2010年6～11月在广州医学院第一附属医院泌尿外科进行经皮肾镜取石术的68例患者术前中段尿培养、术中结石细菌培养、结石红外光谱成分分析结果以及患者术后发生全身炎症反应的情况,并分析上述结果之间以及与患者术后发生全身炎症反应(SIRS)的关系。结果 68例患者术前中段尿培养阳性结果25例(36.76%),阴性43例(63.24%),结石细菌培养阳性结果13例(19.12%),阴性55例(80.88%),其中11例结石细菌培养阳性患者的中段尿培养结果也为阳性。术后结石样本成分经红外光谱分析感染性结石20例(29.41%),非感染性结石48例(70.59%)。共有16例(23.53%)患者术后出现全身炎症反应。结石细菌培养结果与膀胱中段尿培养结果比较具有显著性统计学差异(P<0.05),结石细菌培养阳性与感染性结石具有明显相关性(P<0.05)。而感染性结石与结石细菌培养阳性与术后发生全身炎症反应有关(P<0.05)。结论相对于膀胱中段尿培养,结石细菌培养对于预测感染性结石有较高的准确性,并能更好预测经皮肾镜取石术后SIRS的发生。
Objective To explore the clinical significance of stone bacterial culture and the bladder urine culture in urolithiasis, and to investigate their correlation to the systemic inflammatory response syndrome （SIRS） after percutaneous nephrolithotomy （PCNL）. Methods From June 2010 to November 2011, the clinical data of 68 patients who underwent PCNL in our department were collected and analyzed. Results Bladder urine culture was positive in 25 cases, and stone culture was positive in 13 cases. Both bladder urine culture and stone culture were positive in the same 11 cases. The stone composition was ammonium magnesium phosphate in 20 cases. SIRS was observed in 16 cases after PCNL. There was significant difference be- tween bladder urine culture and stone culture （P^0.05）. Stone culture was correlated with infectious stones （P〈0.05）. Both stone culture and infectious stones were related with SIRS occurrence after PCNL. Conclusion Compared with bladder urine culture, stone bacterial culture can predict infectious stones and SIRS after PCNL more efficiently. The positive stone culture is a risk factor of post-PCNL SIRS.
出处
《现代泌尿外科杂志》
CAS
2013年第1期19-22,共4页
Journal of Modern Urology
基金
卫生部卫生行业科研专项项目(No.201002010)
关键词
细菌培养
感染性结石
尿路感染
全身炎症反应综合征
经皮肾镜取石术
bacterial culture
infectious stone
urinary tract infection
systemic inflammatory response syndrome
percu-taneous nephrolithotomy
