摘要
目的评估心血管高危患者踝臂指数(ABI)与1年全因及心血管死亡率的相关性。方法选择3 179例心血管高危患者,检测静息状态下ABI,以ABI<0.9为低ABI。将患者分为4组:冠状动脉粥样硬化性心脏病(CHD)组、缺血性脑卒中(IS)组、糖尿病(DM)组、极高危(VHR)组。随访1～1.5年,评价ABI与1年全因及心血管死亡率的相关性。结果低ABI发生率为28.2%。低ABI者的全因死亡率及心血管死亡率(14.2%,6.6%)高于ABI正常者(6.5%,2.5%)(P<0.01)。各组低ABI者全因死亡率及心血管死亡率均高于ABI正常者(P<0.01)。DM患者全因死亡及心血管死亡风险均高于其余3组。结论 ABI是死亡率强有力的独立预测因子,其中低ABI患者的1年全因死亡及心血管死亡风险大幅度增加。
Objective To assess the correlation between ankle-brachial index （ABI） and 1-year all-cause and cardio- vascular mortalities in patients with high cardiovascular risk. Methods 3 179 patients with high cardiovascular risk were selected. The ABI indexes at resting state were detected, and ABI 〈 0.9 was regarded as low ABI. The patients were divided into four groups： coronary atherosclerotic heart disease （CHD） group, ischemic stroke （IS） group, dia- betes mellitus （DM） group and very high risk （VHR） group. Then the patients were followed up for 1 to 1.5 years, and the correlations between ABI and 1-year all-cause and cardiovascular mortalities were assessed. Results The inci- dence of low ABI was 28.2%. The all-cause and cardiovascular mortalities （ 14.2%, 6.6% ） in patients with low ABI were obviously higher than those in patients with normal ABI （6.5%, 2.5% ） （P 〈0.01 ）. In each group, the all- cause and cardiovascular mortalities in patients with low ABI were obviously higher than those in patients with normal ABI（ P 〈 0.01 ）. The all-cause and cardiovascular mortality risks in DM group were higher than those in the other three groups. Conclusion ABI is an independent predictor of mortality, and patients with low ABI have a substantial increase in the risk of all-cause and cardiovascular death.
出处
《山东大学学报（医学版）》
CAS
北大核心
2013年第1期53-55,78,共4页
Journal of Shandong University:Health Sciences
关键词
踝臂指数
高危人群
心血管疾病
死亡率
Ankle-brachial index
High-risk group
Cardiovascular diseases
Mortality rate
