摘要
目的探讨支气管肺泡灌洗联合BiPAP对AECOPD伴呼吸衰竭患者病情及血气分析的影响。方法将118例AECOPD患者随机分入对照组与观察组,给予58例对照组患者BiPAP治疗,60例观察组患者接受BiPAP联合支气管肺泡灌洗治疗。比较两组患者入院期间病死率、机械通气率、住院时间以及血气分析指标的差别。结果观察组住院期间病死率和机械通气率分别为1.7%和1.7%,显著低于对照组6.9%和8.6%(P<0.05);观察组与对照组住院时间分别为16.89±2.97 d和26.19±3.28 d,差别具有统计学意义(P<0.05);治疗后观察组血气分析指标PaO2、PaCO2及pH值显著优于对照组(P<0.05)。结论支气管肺泡灌洗联合BiPAP治疗AECOPD可显著改善血气分析指标,改善患者预后。
Objective To explore the influence of bronchoalveolar lavage combined with BiPAP on patients＂ condition and blood gas analysis in the treatment of AECOPD patients complicated with type Ⅱ respiratory failure. Methods 118 AECOPD patients complicated with type Ⅱ respiratory failure were randomly divided into the control group and the experience group. The control group （ n = 58 ） received BiPAP treatment and the experience group （n = 60） were given BiPAP and bronchoalveolar lavage treatment. Mortality, machine ventilation rate, hospital stay and blood gas analysis indexes were compared between the two groups. Results The rates of mortality and machine ventilation in the experience group were 1.7% and 1.7%, which were much lower than those in the control group （6.9% and 8.6% respectively, P 〈0. 05 ）. The duration of hospital stay were 16. 89± 2.97 d and 26. 19±3.28 d respectively in the experience group and the control group with significant difference （P 〈 0. 05 ）. The PH value and levels of PaO2 and PaCO2 in the experience group were superior to the control group after the treatment （ P 〈 0. 05）. Conclusion Bronchoalveolar lavage combined with BiPAP can greatly improve the indexes of blood gas analysis and patients＇prognosis in the treatment of AECOPD patients complicated with type Ⅱ respiratory failure.
出处
《临床肺科杂志》
2013年第2期297-298,共2页
Journal of Clinical Pulmonary Medicine
关键词
慢性阻塞性肺疾病急性发作
支气管肺泡灌洗
无创正压通气
chronic obstructive pulmonary disease at acute exacerbation stage
bronchoalveolar lavage
BiPAP
