摘要
目的探讨体腔热灌注化疗治疗恶性胸水临床疗效。方法 64例随机分为治疗组及对照组各32例,治疗组采用体腔循环热化疗治疗胸水,将化疗药物等(顺铂和地塞米松)用0.9%的生理盐水稀释后加入体腔热灌注机的加热系统中,当加热至42.5℃-43℃时,将药液恒温匀速灌入胸腔,保留24小时引出:对照组行单纯胸腔化疗。结果治疗组33例,CR占69.7%,PR占15.2%。NC占15.2%。总有效率为84.8%,对照组35例:CR占34.3%,PR占25.7%,NC占40%。明显高于对照组60%。结论胸腔内持续恒温循环热灌注治疗明显提高了单纯胸腔化疗的有效率,改善晚期胸水患者的生存质量,毒副作用小,安全性好。
Objective To study the curative effect of body hot perfusion in the treatment of malignant pleural fluid. Methods 64 patients were randomly and evenly divided into the treatment group and the control group. The treatment group used the body hot circu- lation chemotherapy to treat the pleural fluid. The chemotherapy drugs （ cisplatin and dexame.thasone） were diluted in 0. 9% of normal sa- line, and then were put into the heating system, when the liquid was heated to 42.5 ~C - 43 ~C, it was infused into the thoracic cavity at a constant speed and temperature. After 24 hours, the liquid was induced. The control group were given the simple intracavitary chemo- therapy. Results In the treatment group, CR was occupied 69.7%, PR accounted for 15.2%, and NC took up 15.2%. The total effec- tive rate of the treatment group was 84.8%. In the control group, CR accounted for 34.3%, PR accounted for 25.7%, and NC accoun- ted for 40%. The total effective rate of the control group was 60. 0%. The total effective rate was obviously higher in the treatment group than in the control group. Conclusion The hot perfusion at a constant speed and temperature can improve the life quality of patients with malignant pleural fluid and has little side effect and good safety.
出处
《临床肺科杂志》
2013年第2期224-225,共2页
Journal of Clinical Pulmonary Medicine
关键词
恶性胸水
体腔热灌注
malignant pleural fluid
body hot perfusion
