摘要
目的分析2型糖尿病发生早期肾病的影响因素。方法随机选取153例2型糖尿病患者和148例2型糖尿病早期肾病患者,分别检测2组的一般临床生化指标,采用Logistic回归分析探讨2型糖尿病患者发生糖尿病早期肾病的影响因素。结果 2型糖尿病早期肾病组的患者血清中年龄、病程、同型半胱氨酸、超敏C反应蛋白和糖化血红蛋白高于2型糖尿病组,差异有统计学意义(P<0.05)。Logistic回归显示年龄、病程、同型半胱氨酸、超敏C反应蛋白和糖化血红蛋白与2型糖尿病发生早期肾病密切相关。结论 2型糖尿病发生早期肾病是多因素综合作用的结果。
Objective To analyze the influencing factors of early diabetic nephropathy in the patients with type 2 diabetes mellitus. Methods One hundred and fifty-three patients of type 2 diabetes without diabetic ne- phropathy and 148 patients of type 2 diabetes with early diabetic nephropathy were chosen randomly. Each of the groups was examined in the general clinical biochemical indexes. Correlation analysis was conducted to discuss the influencing factors of early diabetic nephropathy in patients with type 2 diabetes mellitus. Results The differences of the age, disease course, homocysteine, high sensitivity C reactive protein, and glycated hemoglobin between the two groups are statistically significant （P ~ 0.05）. Logistic regression analysis showed that age, disease course, homocysteine, high sensitivity C reactive protein and glycated hemoglobin is closely related to early diabetic ne- phropathy of type 2 diabetes mellitus. Conclusion The occurrence of early diabetes nephropathy of type 2 diabetes mellitus is the results of various factors.
关键词
糖尿病
2型
糖尿病肾病
同型半胱氨酸
超敏C反应蛋白
糖化血红蛋白
Diabetes,type 2
Diabetic nephropathy
Homocysteine
High sensitive C reactive protein
Glycosylated hemoglobin
