摘要
目的观察注射用头孢美唑在儿童中重度呼吸系统细菌感染性疾病的临床疗效与安全性。方法将96例呼吸道细菌性感染患儿随机分为两组,头孢美唑组给予注射用头孢美唑治疗,头孢哌酮组给予头孢哌酮治疗,比较两组患者的临床疗效与致病菌的清除率差异。结果①头孢美唑组治疗总有效率为95.56%,明显高于头孢哌酮组(65.22%),P<0.01;②头孢美唑组总致病菌清除率为88.37%,明显高于头孢哌酮组(60.00%),P<0.01;③头孢美唑组不良反应发生率为8.89%,头孢哌酮组为21.74%,P>0.05。结论注射用头孢美唑是治疗儿童中重度呼吸系统细菌性感染的有效、敏感、安全的抗生素,明显优于头孢哌酮。
Objective To observe the clinical effect and safety of injectable cefmetazole in children with moderate to severe bacterial respiratory infection disease. Methods 96 children with bacterial respiratory infection were randomly divided into two groups, with 48 cases in each group. The cefmetazole group was treated with injectable cefmetazole, while the cefoperazone group was treated with cefoperazone. The clinical curative effect and the clearance rate of pathogenic bacteria were compared. Results （1） The total effective rate of the cefmetazole group was 95.56%, obviously higher than 65.22% of the cefoperazone group （P〈0.01）. （2）The total clearance rate of pathogenic bacteria of the cefmetazole group was 88.37%, obviously higher than 60% of the cefoperazone group （P〈0.01）. （3）The adverse reaction rate of the cefmetazole group was 8.89%, and 21.74% of the cefoperazone group （P〉0.05）. Conclusions Injectable cefmetazole is an effective, sensitive, safe antibiotic for children with moderate to severe bacterial respiratory infection, which is significantly superior to cefoperazone.
出处
《临床医学工程》
2013年第1期71-72,共2页
Clinical Medicine & Engineering
关键词
头孢美唑
中重度呼吸系统细菌性感染
疗效
安全性
Cefmetazole
Moderate to severe bacterial respiratory infection
Curative effect
Safety
