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Th17应答在哮喘发病机制中作用的研究进展 被引量：6

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摘要 支气管哮喘是一种T淋巴细胞相关的慢性呼吸系统非特异性炎症性疾病。自从Mosmann等发现以分泌白细胞介素（interleukin，IL）-2、干扰素γ（interferonγ，IFN-γ）为特征的辅助性T淋巴细胞（helper T lymphocyte，Th）1和以分泌IL-4、IL-5、IL-13为特征的Th2细胞以来，Th1／Th2应答失衡一直被认为是经典的发病机制而应用于支气管哮喘的研究中。
作者 赵燕 程晓明 王长征 王导新
机构地区 重庆医科大学附属第二医院呼吸内科 第三军医大学新桥医院呼吸内科
出处 《重庆医学》 CAS CSCD 北大核心 2013年第2期216-218,共3页 Chongqing medicine
基金 国家自然科学基金资助项目(2010A246)
关键词 哮喘 T淋巴细胞 白细胞介素类
分类号 R562.25 [医药卫生—呼吸系统]
  • 相关文献

参考文献25

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二级参考文献28

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共引文献37

同被引文献75

  • 1龚臣,邓静敏.Th17/Treg在支气管哮喘发病机制中的作用及研究进展[J].中华哮喘杂志（电子版）,2013,7(3):41-45. 被引量：54
  • 2李晓丹,许力军,刘超英,邹奇,丛中凰,王满,张洪泉.联合雾化吸入治疗急性发作期支气管哮喘患者的效果评价[J].吉林大学学报（医学版）,2011,37(6):1120-1123. 被引量：13
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  • 4Park H,Lee CM,Jung ID,et al. Quercetin regulates Thl/ Th2 balance in a murine model of asthma [J]. Internation- al immunopharmacology, 2009,9 (3) : 261-267.
  • 5Borish L,Steinke JW. Interleukin-33 in asthma: how big of a role does it play?[J]. Current Allergy And Asthma Re- ports,2011,11 (1) : 7-11.
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引证文献6

二级引证文献74

重庆医学
2013年 第2期

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