摘要
目的研究一种方便、快速合成丙酮缩氨基脲(AS)的方法。方法以盐酸氨基脲和丙酮为原料,室温下超声辐射协助合成丙酮缩氨基脲。考察原料配比、超声辐射频率和反应时间对反应产率的影响。结果在最佳反应条件下(nSHC∶nacetone=1∶10,超声频率59kHz,反应时间40min)合成了丙酮缩氨基脲,收率可达85%。结论此法与常规的加热反应法相比,反应时间短,产物收率高,操作简单。
Aim To seek a convenient, rapid synthetic method of acetone semicarbazone（AS）. Methods Acetone semicarbazone is synthesized under ultrasonic irradiation at room condition by u- sing semicarbazide hydrochloride （SHC） and acetone as raw materials. The effect of reactants molar ratio, ultrasound irradiation frequency and reaction time on the yields of acetone semicarhazone syn- thesis is studied. Results Acetone semicarbazone is synthesized under the optimum synthetic condi- tions （molar ratio of semicarbazide hydrochloride to acetone is 1 ： 10 （nsnc ： n = 1 ： 10）, and the ultrasonic radiation frequency is 59 kHz, the irradiation time is 40 min）. The yield is over 85%. Con- clusion Compared with the conventional heating reactions, this method features shorter reaction time, higher product yields and easier operation.
出处
《宝鸡文理学院学报（自然科学版）》
CAS
2012年第4期33-35,共3页
Journal of Baoji University of Arts and Sciences(Natural Science Edition)
基金
庆阳市科技局基金资助项目(G2011-15)
关键词
超声波
丙酮缩氨基脲
盐酸氨基脲
ultrasound irradiation
acetone semicarbazone
semicarbazide hydroehloride
