期刊文献+

南京市2011年手足口病流行病学及病原学特征分析 被引量:48

Epidemiology and Etiology of Hand,Foot and Mouth Disease in Nanjing 2011
暂未订购
导出
摘要 目的:分析南京市2011年手足口病的流行病学及病原学特征。方法:利用国家疾病监测信息系统结合实验室确诊阳性样本信息对2011年南京市手足口病相关资料进行描述性流行病学分析。结果:2011年全市共报告手足口病15694例,其中重症877例,死亡3例。年均报告发病率为193.54/10万,发病高峰集中在4~7月;主城区发病高于城郊区县;发患者群以5岁以下的幼托及散居儿童为主,男性发病高于女性。全市共报告实验室检测病例1757例,普通病例以EV71和CoxA16共同主导流行,重症病例和死亡病例以EV71为流行优势株。结论:南京市2011年手足口病流行存在明显的季节、人群和地区差异,5岁以下幼托和散居儿童是手足口病防控的重点人群。主要致病病原为EV71和CoxA16,深入开展手足口病流行病学和病原学研究,将有助于更好的防控和治疗手足口病。 Objective:To analyze the etiological and epidemiological characteristics of hand,foot and mouth disease(HFMD) in Nanjing,2011.Method:The data of HFMD from the national Disease Surveillance Information Reporting System and microbiological laboratory was analyzed by descriptive and inferential statistics.Result:A total of 15 694 HFMD cases,including 877 severe cases and 3 death cases,were reported during 2011.The average incidence rate of HFMD was 193.54 per million.The peak incidence occurred during the period from April to July.The urban area had a significant distribution dominance comparing with other rural districts.Most of the cases were children under 5 years.The number of male cases was larger than that of the female.Among the reported cases,1757 were laboratory confirmed.The HFMD cases with mild symptoms were caused mainly by EV71 and Cox A16,while the severe and death cases were mainly caused by EV71 infection.Conclusion:The incidence of HFMD in Nanjing has significant seasonal,regional,sex and age-specific differences.The key population for the prevention and control of HFMD is the children under 5 years in scattered home and preschool.The main pathogens were EV71 and Cox A16.It would improve prevention and control measures by deeper research on epidemiology and etiology of HFMD.
出处 《中国医学创新》 CAS 2013年第1期89-91,共3页 Medical Innovation of China
关键词 手足口病 流行病学 肠道病毒71型 柯萨奇病毒A16型 Hand foot and mouth disease Epidemiology Enterovirus 71 Coxsackievirus A16
  • 相关文献

参考文献11

二级参考文献50

  • 1陈宗波.人类肠道病毒71型感染的研究进展[J].中华儿科杂志,2005,43(6):428-430. 被引量:102
  • 2薛家芹,杨会利,陈勇,高荣涛,李广法.2003年泰安市部分手足口病住院病例分析[J].预防医学论坛,2005,11(6):676-677. 被引量:30
  • 3Robinson CR,Doanc FW,Rhodes AJ.Report of an outbreak of febrile illness with pharyngeal lesion and exanthen:Totonto,1957 Isolation of group A Coxsackie virus[J].Canad Med Assoc J,1958,79(3):615-621.
  • 4周正伍,李凡.医学微生物学[M].6版.北京:人民卫生出版社,2005:274-275.
  • 5Melnick JL.Nterovirus type 71 infections:a varied clinical pattern sometimes mimicking paralytic poliomyelitis[J].Rev Infect Dis,1984,6(Suppl 2):S387-390.
  • 6Bendig JW,Fleming DM.Epidemiological,virological,and clinical features of an epidemic of hand,foot and mouth disease in England and Wales[J].Commun Dis Rep CDR Rev,996,6(6):R81-86.
  • 7Chan LG,Parashar UD,Lye MS,et al.Deaths of children during an outbreak of hand,foot,and mouth disease in Sarawak,Malaysia[J].Clin Infect Dis,2000,31(3):678 -683.
  • 8Ho M,Chen ER,Hsu KH,et al.An epidemic of enterovirus 71 infection in Taiwan[J].New England Journal of Medicine,1999,341(13):929-935.
  • 9Schmidt NJ,Lennette EH,Ho HH.An apparently new entero Virus isolated from patients with disease of the central ner Vous system[J].J Infect Dis,1974,129(3):304-309.
  • 10Lin TY,Chang LY,Hsia SH,et al.The 1998 entero virus 71 outbreak in Taiwan:pathogenesis and management[J].Ciin Infect Dis,2002,34(Suppl 2):S52-57.

共引文献606

同被引文献428

引证文献48

二级引证文献370

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部