摘要
A series of some new tetrazolo[1,5-a]quinoline based tetrasubstituted imidazole derivatives 6a-i have been synthesized by a reaction of tetrazolo[ 1,5-a]quinoline-4-carbaldehyde 3a-d, benzil 4, aromatic amine 5a--c and ammonium acetate in the presence of iodine through one-pot multi-component reaction （MCR） approach. All the derivatives were screened for antimicrobial and antituberculosis activities and results worth further investigations.
A series of some new tetrazolo[1,5-a]quinoline based tetrasubstituted imidazole derivatives 6a-i have been synthesized by a reaction of tetrazolo[ 1,5-a]quinoline-4-carbaldehyde 3a-d, benzil 4, aromatic amine 5a--c and ammonium acetate in the presence of iodine through one-pot multi-component reaction （MCR） approach. All the derivatives were screened for antimicrobial and antituberculosis activities and results worth further investigations.
