摘要
对30例原发性肝癌患者进行49人次肝动脉灌注化疗和栓塞。19例作灌注化疗加明胶海绵栓塞综合治疗,栓塞后造影可见周围或近端肝动脉栓塞,随访性血管造影见肿瘤血管减少或完全消失,肿瘤缩小,肿瘤坏死区扩大;另11例作单纯性灌注。所有栓塞的病例均有栓塞后综合征,平均存活期半年。灌注化疗加栓塞综合治疗优于单纯性灌注化疗。本文就肝动脉灌注化疗和栓塞的治疗价值、栓塞后综合征、并发症和禁忌症及影响治疗的因素进行讨论。
Fourty-nine hepatic artery infusions (HAI) and embolizations (HAE) were performed on 30 patients with primary liver cancer. Nineteen of them were treated by HAI and HAE in Combination with gelfoam. Peripheral or proximal embolization could be seen on postembolizative arteriograms. Follow-up angiography showed that tumor vessels diminished or completely disappeared and decrease in size and increased the necrotic area of the tumor. Of them 11 were treated by HAI with fluorouracil (5-Fu) and mitomycin-C(MMC) and cisplatin (DDP). The postembolization syndrome, e. g, nausea, vomiting, abdominal pain and fever was observed in all cases. Comparison revealed that HAI and HAE in combination was superior to HAI alone in therapeutic effects. The overall mean survival time is 6 months after the HAE started. The therapeutic effect, postembollzation syndrome, complications and contraindications of HAE and factors affecting the therapeutic effect were discussed.
出处
《安徽医科大学学报》
CAS
1991年第2期128-132,共5页
Acta Universitatis Medicinalis Anhui
关键词
肝肿瘤
肝动脉
输注
栓塞
liver neoplasms/ther
hepatic artery + hepatic arterial infusion, intra-arterial
embolization, therapeutic
