摘要
目的 :探讨睫状神经营养因子 (CNTF)对骨骼肌细胞的直接营养作用 ,从而为神经肌肉系统损伤和退行性病变的治疗提供新的思路。结果 :CNTF可以促进体外培养的L6 TG肌母细胞和新生SD大鼠原代骨骼肌细胞增殖。结论 :CNTF对体外骨骼肌细胞具有营养作用。CNTF的神经和肌肉双重营养性能使其可能在神经肌肉损伤和退行性病变的治疗上发挥重要作用。
Aim: To study the direct trophic function of CNTF on muscle, and to explor new methods for nerve muscle injury and retrogression.Results:CNTF can enhance the proliferation of L6 TG cells and newborn SD rat primary skeletal muscle cells in culture.Conclusion:CNTF is of trophic function on muscle cells in culture. The neurotrophic and myotrophic effect of CNTF may play an important role in the treatment of nerve muscle injury and retrogression.
出处
《中国应用生理学杂志》
CAS
CSCD
2000年第1期59-62,共4页
Chinese Journal of Applied Physiology
关键词
骨骼肌细胞
增殖
神经肌肉疾病
CNTF
cilliary neurotrophic factor(CNTF)
skeletal muscle cells
proliferation
