摘要
目的 对常用的 3种降纤药物 :东菱克栓酶、EW-速效溶栓清、精制蝮蛇抗栓酶治疗急性缺血性脑血管病进行比较。 方法 对 1 997年 6月～ 1 998年 1 2月 ,发病 1周内 ,急性缺血性脑血管病 ,按全国第四届脑血管病会议制定的标准 ,在可比的条件下 ,甲组 2 3例 ,用东菱克栓酶治疗 ;乙组 2 8例 ,用 EW-速效溶栓清治疗 ;丙组 2 7例 ,用精制蝮蛇抗栓酶治疗。进行临床与实验室观察。 结果 3组疗效临床评分有效率各为 :95.65%、 92 .86%、 88.89%。实验室检查纤维蛋白原均有下降 ,但以甲、丙两组下降较为明显。观察期间发现出血、过敏等副作用。 结论 3种常用降纤药物对急性期缺血性脑血管病均有疗效 ,如患者纤维蛋白原增高 ,选东菱克栓酶或精制蝮蛇抗栓酶治疗为宜。
Objective Purpose we compared effect of three defibrasely medicines in common use(batroxobin EW-lysisthrombusase refined ahyly-santinfaretase) which are used in acute cerebral ischemia Methods Patients had an attack of ischmic stroke in a week from July 1997 to December 1998 are devided into groups(A,23;B,28;C,27) randomly up to standard of the Fourth Natural Cerebral Desease Meeting Results Three groups patients are treated by batroxobn,Ew-lysisthrombusase,refined ahylysantinfaretase respectively and investigated in clinic and experiment Effective rates of three groups are 95 65%,92 86%,88 89% respectively in clinic Fibrinogen in all groups are decreased Some side effect such as haemorrhage,allergy are found Conclusions Three defibrases are effective in treatment of acute cerebral ischemia Batroxobin and refined ahylysantinfaretase are selected to cure the patients who have high level of fibrinogen
出处
《蛇志》
2000年第1期18-19,共2页
Journal of Snake
关键词
缺血性脑血管病
降纤药物
疗效试验
ahylysantinfaretase,lysisthrombus,ischemic cerebro vasculor desease
