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Alzheimer病线粒体DNA突变分子生物学研究进展 被引量:3

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摘要 脑能量代谢降低为AD发病的危险因素之一 ,而线粒体是细胞能量储存和供给的重要场所。近年研究认为 ,线粒体DNA突变与AD的发病有关 。
作者 马秋兰 陈彪
出处 《国外医学(神经病学.神经外科学分册)》 2000年第3期148-151,共4页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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参考文献10

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同被引文献36

  • 1曾昭惠,张宗玉.自由基对线粒体DNA的氧化损伤与衰老[J].生物化学与生物物理进展,1995,22(5):429-432. 被引量:53
  • 2王月华,杜冠华.复方小续命汤抗AD有效成分组研究[J].中成药,2005,27(9):993-996. 被引量:29
  • 3包雅琳 陈秀华.中华医学会第一届神经病学论坛纪要[J].中华神经科杂志,2000,33(3):135-135.
  • 4史庭慧 .阿尔茨海默病.见:刘汴生,张思雄主编 .实用临床老年病学[M].第一版,北京:中国医药科技出版社, 2001, 291-300.
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  • 7Wyss-Coray T.Lin C. Sanan D.A.Chronic Overproduction of Transforming Growth Factor-beta 1 by Astrocytes Promotes Alzheimer's Disease-Like Microvascular Degeneration in Transgenic Mice[J].American Journal of Pathology 2000,156(1):139.
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  • 9Richard J. Porter, M.R.C.et al.Cognitive Deficit Induced by Acute Tryptophan Depletion in Patients With Alzheimer's Disease[J].The American Journal of Psychiatry 2000,157(4): 638.
  • 10Yu-Min Kuo Tyler A. et al.Elevated Aβ42 in Skeletal Muscle of Alzheimer Disease Patients Suggests Peripheral Alterations of AβPP Metabolism[J] . American Journal of Pathology 2000,156(3): 797.

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