摘要
目的 了解甲状腺功能亢进症 (甲亢 )合并甲状腺癌的状况。方法 对本院 1983年 1月～ 1998年 6月 ,接受手术方法治疗的 394例甲亢和经手术病理诊断的 2 45例甲状腺癌一并进行回顾性分析。结果 共发现甲亢合并甲状腺癌 12例 ,占甲亢的 3.0 % (12 /394) ,占甲状腺癌的 4.9% (12 /2 45 ) ;Graves病合并甲状腺癌 6例 ,毒性结节性甲状腺肿合并甲状腺癌 6例。12例患者中 ,甲状腺呈弥漫性肿大 3例 ,弥漫性肿大伴单结节 3例 ,多结节性肿大 6例 ;8例术前进行了甲状腺核素检查 ,5例肿瘤位于“冷结节”处 ,1例有位于“热结节”处 ,2例未见结节 ,此 2例为隐匿性病灶 (直径小于 1cm)。7例肿瘤直径小于 1cm,1例有转移现象发生 ;4例肿瘤直径大于 3cm,其中 3例发现局部或远处转移。4例转移者中 ,滤泡细胞癌 2例 ,乳头 -滤泡细胞癌 1例 ,乳头状癌 1例。结论 甲亢合并甲状腺癌达 3%～ 5 %左右 ,高于人群中甲状腺癌发病率 ,肿瘤体积多较小 ,多位于不吸收碘的“冷结节”区 ,但当肿瘤直径大于 3cm时 ,易出现转移。
A retrospective study has been carried out to evaluate the prevalence of coincidence with hyperthyroidism and thyroid carcinoma. Methods 394 patients underwent surgery for hyperthyroidism and 245 patients suffered from thyroid cancer were chosen for the study in our hospital from January 1983 to June 1998. Results Thyroid cancer and hyperthyroidism coincided in 12 patients.The incidence of thyroid cancer was 3.0%(12/394) in hyperthyroidism,and the incidence of hyperthyroidism was 4.9% in thyroid cancer.There were 7 female and 5 male,with a diffuse goiter(n=3),a diffuse goiter with a cold nodule (n=3),multinodular goiter (n=6).Among the 12 patients,7 patients had an occult thyroid cancer with a diameter of 1 cm or less,most of them with papillary carcinoma,less frequently had metastases,4 patients had thyroid cancer with a diameter of 3 cm or more,and 3 patients had metastases. Conclusions The prevalence of coincidence with thyroid cancer and hyperthyroidism is more than that of thyroid cancer in population.Diagnostics for exclusion of thyroid cancer is required carefully even in the presence of hyperthyroidism.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2000年第3期273-275,共3页
Acta Academiae Medicinae Sinicae
