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亚低温联合经侧裂手术治疗高血压脑出血的临床研究 被引量:6

Clinical Research of mild hypothermia combined with surgery via sylvian fissure approach on hypertensive cerebral hemorrhage
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摘要 目的探讨亚低温联合经侧裂手术治疗高血压脑出血的临床疗效。方法选择高血压脑出血患者60例按照入院时间先后顺序分为对照组与观察组各30例,对照组给予常规治疗,观察组在常规治疗基础上给予亚低温联合经侧裂血肿清除术治疗,比较两组患者神经功能缺损(CSS)评分、治疗效果与治疗后随访3个月Barthel指数。结果观察组的有效率为83.3%,病死率为16.7%,显著优于对照组的46.7%和53.3%(P<0.05);观察组在治疗后7、14、21 d的CSS评分较治疗前显著降低,对照组在治疗14、21 d后显著降低(P<0.05);且治疗后7、14、21 d观察组评分显著低于对照组(P<0.05)。随访3个月后,Barthel指数分级比较,观察组显著优于对照组(P<0.05)。结论亚低温联合经侧裂手术治疗高血压脑出血可有效降低脑出血的病死率与致残率,提高患者的生存质量。 Objective To discuss the clinical effects of mild hypothermia combined with surgery via sylvian fissure approach in patients with hypertensive cerebral hemorrhage. Methods Sixty patients with hypertensive cerebral hemorrhage were randomly divided into the observation group(30 cases) and the control group(30 cases),the control group were given conventional medical the-rapy,and the observation group were given mild hypothermia combined with surgery via sylvian fissure approach based on the conventional medical therapy,then contrasted the CSS,clinical effects and 3 months Barthel index between the two groups. Results The effective rate and case fatality rate of the observation group were 83.3% and 16.7%,significantly better than the control group(46.7% and 53.3%)(P0.05);the CSS at 7,14 and 21d after the treatment were significantly lower than before in the observation group,but only at 14 and 21d after the treatment were significantly lower than before in the control group(P0.05),and CSS at 7,14,21d after the treatment in the observation group were significantly lower than in the control group(P0.05).The Barthel index classification of the observation group was significantly better than of the control group 3 months after the treatment(P0.05). Conclusion Mild hypothermia combined with surgery via sylvian fissure approach can effectively reduce the mortality and morbidity of cerebral hemorrhage,and improve the quality of life of patients.
作者 董鑫 刘增强
机构地区 中铁
出处 《临床军医杂志》 CAS 2012年第6期1319-1321,共3页 Clinical Journal of Medical Officers
关键词 亚低温 脑出血 高血压 mild hypothermia cerebral hemorrhage hypertension
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