摘要
目的 探讨软性接触镜 (SCL)相关性角膜新生血管形成 (CNV)的流行病学、临床表现、危险因素与预防措施。方法 对 1995年 7月～ 1997年 6月验配SCL的屈光不正患者CNV发生情况进行回顾性分析。结果 配前检查时 :重配者中 ,CNV阳性者 (>0 6mm)占 7 4% ,多位于角膜上下部的浅基质层 ,症状轻微 ,其中 5 1 9%有长戴史 ,48 2 %有配适问题 ,74 1%护理不当 ,无定期复查者 ;初配者中 ,0 4%有轻度CNV。配SCL后 ,能经常复查者占 6 5 2 % ,其中CNV阳性者占 2 4% ,仍分别有 32 9% ,5 7 9%有配适与护理不当问题。按FDA标准 (>1 5mm) ,最后的CNV发生率 0 4%在SCL所有并发症中占 11 3 % ,较重配者配前检查时 (0 8% )显著降低 (P <0 0 1)。结论 提高配适水平 ,避免长戴与定期复查可有效地降低SCL相关性CNV发生率。
ObjectiveTo evaluate the prevalence,clinical presentation and associated risk factors of corneal neovascularization(CNV) associated with soft contact lens(SCL) wear and explore methods for its prevention.MethodsA retrospective study was performed to review the charts of CNV in the ametropic patients fitting SCL from July 1995 to June 1997.ResultsIn the prefit ocular examinations,7 4% of the refitter had CNV(>0 6?mm).The CNV was mainly located in the superior and inferior anterior stroma,most patients had no obvious symptoms,51 9% with overnight wear at least part of the time,48 2% had poor fit,74 1% had inappropriate lens care,and none had regular follow ups.0 4% of the new fitter had mild CNV.After the SCL fitting,65 2% of all the SCL wearers could comply with follow ups regularly,of which 2 4% had CNV.32 9% of the CNV patients had poor fit and 57 9% had inappropriate lens care.According to FDA standard(>1 5?mm),the last CNV incidence 0 4%,which accounted for 11 3% of all the SCL complications,was significantly lower than that of the refitter(0 8%) in the prefit examinations ( P <0 01).ConclusionThe incidence of SCL associated CNV could be reduced through enhancing SCL fitting and extent of care,and with regular follow ups.
出处
《眼科研究》
CSCD
2000年第2期157-159,共3页
Chinese Ophthalmic Research
关键词
接触镜
并发症
角膜新生血管
CNV
contact lens complications corneal neovascularization
