摘要
目的探讨腹腔镜下子宫肌瘤剔除术中先行子宫动脉上行支血流阻断对卵巢储备功能的影响。方法具有完整随访资料的子宫肌瘤患者119例随机分为2组,腹腔镜下子宫肌瘤剔除术联合子宫动脉上行支阻断术组(试验组)64例和腹腔镜下子宫肌瘤剔除术组(对照组)55例,比较2组术前,术后2个月、6个月、1年和2年血清雌二醇(serum estrodiol,E2)、促卵泡生成素(follicle-stimulating hormone,FSH)和黄体生成素(luteinizing hormone,LH)的水平,观察性激素及卵巢体积的变化。结果术后2个月试验组FSH升高,与术前比较差异有统计学意义(P<0.05),术后6个月、1年、2年FSH水平与术前相比,差异无统计学意义(P>0.05)。试验组各个时间点的E_2水平差异无统计学意义(P>0.05)。2组术前术后卵巢体积差异无统计学意义(P>0.05)。结论腹腔镜下子宫肌瘤剔除术中应用阻断子宫动脉上行支的血流辅助治疗安全有效,对卵巢功能的影响是暂时的、可逆的,具有一定的临床推广价值。
Objective To investigate the ovarian function after laparoscopic myomectomy combined with ascending branch of uterine artery occulusion. Methods A total of 119 patients with uterine fibroids with integrated follow- up data were divided into two groups, study group was performed laparoscopic myomectomy combined with ascending branch of uterine artery occulusion, control group was performed laparoscopic myomectomy, among which 64 cases were in study group and 55 cases in control group. The serum estrodiol （ E2 ）, follicle - stimulating hormone （FSH） and luteinizing hormone （ LH ） levels were measured in the two groups preoperatively, 2 months, 6 months, 1 year and 2 year post - operatively. The variation of homorne and ovarian volume were investigated. Results Compared with preoperative, serum FSH level increased in study group 2 months postoperatively （P 〈 O. 05 ）, but not in study group 6 months, 1 year and 2 year postoperatively （ P 〉 0. 05 ）. There were no significant differences in the level of E2 at each time point in study group （ P 〉 0.05 ）. There were no significant differences in ovarian volume before and after operation in both group （ P 〉 0. 05 ）. Conclusion Laparoscopic myomectomy combined with ascending branch of uterine artery occulusion is safe and efficient and is worthy of spreading clinically.
出处
《河北医科大学学报》
CAS
2012年第12期1405-1408,共4页
Journal of Hebei Medical University
