摘要
目的探讨外科病房深部真菌感染的危险因素,为制定深部真菌感染防治策略提供依据。方法采用回顾性调查方法,收集2002年4月～2012年8月外科病房深部真菌感染132例患者的临床资料。分析发生医院深部真菌感染的危险因素。结果 132例患者共分离出真菌157株,深部真菌感染以白色念珠菌居首位,占65.61%,二种以上真菌混合感染者占14.39%。深部真菌感染的疾病主要有重症急性胰腺炎、肝胆胰恶性肿瘤。患者年龄≥60岁、基础病≥3个、人工机械通气、使用≥2种抗菌药物、留置导尿、全胃肠外营养等11个因素是外科病房深部真菌感染的相关因素。结论深部真菌感染是外科病房常见的并发症,需及时控制危险因素,合理使用抗生素,减少不必要的诊疗操作。警惕深部真菌感染,及早给予经验治疗,做到早期诊断,规范治疗。
Objective To investigate the risk factors of deep fungal infection in surgical ward,and provide the basis for generating the strategy to control and treat the deep fungal infection.Methods The clinical data of 132 cases of patients with deep fungal infected from April 2002 to August 2012 in the surgical ward were collected by the method of the retrospective survey.The risk factors of nosocomial deep fungal infections were analyzed.Results Among 132 patients,157 stains were isolated,and most of them were candida albicans which accounting for 65.61% in the first.And the rate of more than two kinds mixed fungal infection was 14.39%.Deep fungal infections always included severe acute pancreatitis and malignancy of hepatobiliary or pancreatic.There were 11 factors,such as age≥ 60 year,underlying disease ≥ 3,mechanical ventilation,the kind of antimicrobial drugs≥ 2,use of indwelling catheterization,total parenteral nutrition were the correlation factors of surgical wards deep fungal infection.Conclusion Deep fungal infection is a common complication in the surgical ward.Risk factors should be controlled timely,with the use of antibiotics rationally and reducing the unnecessary operation in the clinic.And Clinic should keep the wary of deep fungal infections,give the empirical treatment early,in order to make the diagnose early and standardize the treatment.
出处
《中国当代医药》
2012年第36期54-55,57,共3页
China Modern Medicine
基金
河南省濮阳市2012年科技计划立项课题(项目编号:120485)
关键词
深部真菌感染
外科病房
危险因素
感染控制
Deep fungal infections
Surgical ward
Risk factors
Infection control
