摘要
目的探讨奥美拉唑联合奥曲肽治疗肝硬化并上消化道出血的疗效。方法将临床确诊的64例肝硬化并上消化道出血患者按治疗方法不同随机分为对照组和观察组各32例,对照组给予奥美拉唑治疗,观察组在对照组基础上加用奥曲肽,观察两组治疗后疗效。结果对照组和观察组治疗后总有效率分别为75.00%和93.75%,两组比较差异有统计学意义(P<0.05);观察组平均止血时间、住院时间均显著短于对照组,平均血红蛋白上升程度显著高于对照组(P<0.05)。结论奥美拉唑联合奥曲肽治疗肝硬化并上消化道出血可明显提高患者的止血效果,且并发症少,值得推广应用。
Objective To investigate the effect of omeprazole combined with octreotide on the treatment of upper alimentary tract hemorrhage in liver cirrhosis. Methods Sixty-four patients with upper alimentary tract hemorrhage in liver cirrhosis were randomly divided into the control group and observation group, with 32 patients in each group, patients in control group only received omeprazole, while patients of observation group received octreotide on the basis of the control group. Results After treatment, the effective rate of control group and observation group were 75.00% and 93.75%, there was statistically significant difference between two groups （P 0.05）; the hospital stay and haemostasis time of observation group were significantly superior to control group, and the level of hemoglobin was significantly superior to control group （P 0.05）. Conclusion Combined treatment with omeprazole and octreotide is effective for upper alimentary tract hemorrhage in liver cirrhosis, it is safe and worthy of being extended in clinics.
出处
《中国当代医药》
2012年第34期74-75,共2页
China Modern Medicine
关键词
奥美拉唑
奥曲肽
肝硬化
上消化道出血
Omeprazole
Octreotide
Liver cirrhosis
Upper alimentary tract hemorrhage
