摘要
目的:分析南京医科大学第一附属医院抗菌药近5年用药现状和发展趋势,并结合样本耐药菌株耐药率变化,为该类药物管理和临床合理应用提供参考。方法:对2007～2011年间该院抗菌药品种、金额、用药频度(DDDs)及细菌耐药率,进行回顾性分析。结果:该院抗菌药5年来消耗金额呈上升趋势,用药频度逐年下降,细菌耐药率呈缓慢上升趋势。结论:近年细菌耐药率增长迅速,抗菌药临床使用量大,用药频度逐年下降。该院临床抗菌药品用药趋于合理。
Objective：to analyze the present situation and development trend of anti-infection drugs in Jiangsu Provincial People＇s Hospital in recent 5 years,and to provide reference for the drugs procurement,supply and rational clinical application.Methods：The hospital information system（HIS） was used during 2007-2011.Drugs varieties,amount, drugs use frequency（DDDs） and the rate of resistant bacteria were retrospectively analyzed.Results：The anti-infection drugs consumption,varieties and amount were rising in the last five years.The drugs frequency and resistant bacteria increased first,and then dropped.The drug resistance in sample bacteria,pseudomonas aeruginosa declined,and klebsiella pneumonia and escherichia coli decreased first,and then increased.Conclusion：Clinical anti -infection drugs were widely used,and the resistant bacteria presented the trend of a rapid growth,but the dosage and frequency droppetl.The clinical use of antimicrobial drugs was more and more reasonable in our hospital.
出处
《药物流行病学杂志》
CAS
2012年第11期552-555,共4页
Chinese Journal of Pharmacoepidemiology
基金
江苏高校优势学科建设工程资助项目(编号:JX10231081)
