摘要
人体胚胎干细胞是一类具有自我更新能力的多潜能细胞,在一定条件下,可分化成超过200种人体细胞类型,它在发育生物学和再生医学中具有重要的研究价值。其多潜能性使得一系列疾病,包括癌症、阿尔茨海默病和帕金森病的治疗看到了希望。而胚胎干细胞蛋白质组学的研究对揭示胚胎干细胞增殖和分化的机制以及其多潜能的维持具有重大意义。在此,总结在过去几年中已报道的部分关于人体胚胎干细胞蛋白质组学研究取得的进步及其对人体胚胎干细胞研究的促进作用。
Human embryonic stem cell（hESC）is a group of pluripotent cells with self-renewal capacity,which can differentiate into more than 200 kinds of human cell types under certain conditions,and has important research value in developmental biology and regenerative medicine.Pluripotency makes cure of a range of diseases such as cancer,Alzheimer disease and Parkinson disease possible.Embryonic stem cell proteomics research plays an important role in revealing embryonic stem cell proliferation and differentiation mechanisms as well as the maintenance of the pluripotent.Here is to make a summary of some research achievements of human embryonic stem cells proteomics and their role in promoting research in hESC reported in the past few years.
出处
《医学综述》
2012年第23期3939-3941,共3页
Medical Recapitulate
基金
国家"重大新药创新"科技重大专项课题(2011ZX09102-101-03)
