摘要
气道慢性炎症性疾病如慢性阻塞性肺疾病、支气管哮喘等是在各种内外界刺激因素作用下由气道固有细胞、炎症细胞和炎症因子参与的非特异性炎症性疾病。目前,人们已经发现6个IL-17家族成员,它们在慢性气道炎症性疾病的发展中发挥重要作用。故深入认识IL-17家族与慢性气道炎症性疾病的关系将为临床治疗提供新的思路。
Chronic airway inflammatory diseases, such as chronic obstructive pulmonary disease and bronchial asthma, are non-specific inflammatory diseases, in which airway intrinsic cells, inflammatory cells and cytokines involved under various internal and external stimuli factors. So far, 6 members of IL-17 cytokine family have already been described, playing crucial roles in the development of the chronic airway inflammatory diseases. Therefore, further study on the relationship between IL-17 cytokine family and the chronic airway inflammatory diseases will provide new ideas for the treatment of these diseases.
出处
《国际免疫学杂志》
CAS
2013年第1期45-48,共4页
International Journal of Immunology
关键词
IL-17家族
气道慢性炎症
慢性阻塞性肺疾病
支气管哮喘
IL-17 cytokine family
Chronic airway inflammation
Chronic obstructive pulmonary disease
Bronchial asthma