摘要
目的调查研究导致新生儿溶血病的意外抗体分布情况,为诊断和治疗提供支持。方法按照《全国临床检验操作规程》对573例病理性黄疸患儿标本进行溶血三项试验和血清胆红素测定,同时进行意外抗体筛选,阳性标本采用经典抗球蛋白法鉴定抗体特异性。结果共检出意外抗体阳性标本38例(6.63%),其中Rh系统35例(92.1%)、MNS系统2例(5.3%)、Duffy系统1例(2.6%)。结论意外抗体的筛查和鉴定有助于新生儿溶血病的及时诊断和治疗,对提高生育质量具有重要意义。
Objective To investigate unexpected antibodies distribution in hemolytic disease of newborn.Methods Five hundred and seventy-three blood samples of newborn were detected.Hemolysis and bilirubin were tested according to National Guide to Clinical Laboratory Procedures.The unexpected antibodies were identified by classic indirect antiglobulin test.Results Thirty-eight （6.63%） samples were positive by antibody screen test.The unexpected antibodies included 35 cases （92.1%） Rh system antibodies,2 cases （5.3%） MNS system antibodies and 1 case （2.6%） Duffy system antibody.Conclusion Unexpected antibodies detection is helpful for clinical diagnosis and treatment of hemolytic disease of newborn.
出处
《中国当代医药》
2012年第33期78-79,共2页
China Modern Medicine
关键词
新生儿溶血病
血型
意外抗体
检测分析
Hemolytic disease of newborn
Blood group
Unexpected antibodies
Investigation
