摘要
我院1975—1985年收治1158例肺癌,对其中800例中、晚期肺癌临床进行观察,了解肺癌的病理类型和转移特点。本组病例以鳞癌的发病率最高58.5％(468/800例)。鳞癌转移到淋巴结、骨骼、脑为多。胸腔积液合并肺不张、上腔静脉压迫综合征、声音嘶哑(喉返神经受侵致声带麻痹)也是鳞癌多见。小细胞未分化癌16.9％(135/800例),转移到肝脏、淋巴结占多数。腺癌13.0％(104/800例),以导致胸腔积液为最多。本组病例,出现重要器官转移者,中位生存期平均6个月。转移到某器官,当表现出某一器官的症状时,给予适当的化学药物治疗或放射治疗,仍可缓解症状,延长生存期。临床工作者,对中老年患者就诊时,若发现锁骨上区有淋巴结肿大,局限性骨骼疼痛;声音嘶哑,无热性胸腔积液等无原因可查者,均应警惕肺癌转移的可能。必须追查病史,进一步检查。肺癌扩散对患者严重危害,急待同道们共同探索一种能抑制癌肿扩散的防治方法。
From 1975 to 1985, 1158 cases of primary lung cancer were treated inour hospital. Among them, 800 progressing and advanced cases were studied for the pathologic classification and the characteristics of metastasis.In this group, the incidence of squamous cell cancer was highest (58.5% ,468/800). Met-astases of squamous cell cancer to lymph nodes, bone, brain, etc. were most common. Pl-eural effusion complicated with atelectasis, superior vena cava syndrome and hoarseness (par- alsis of vocal cord due to involvement of recurrent laryngeal nerve) were also common in squamous cell cancer. The incidence rate for small cell anaplastic carcinoma was 16.9% (138/ 800), most metastases were observed in the liver and lymph nodes, the incidence rate for adenocarcinoma was 13% (104/800), the main metastases presented in pleural effusion. In this series most patients had metastases to important organs, the median survival time was 6-8 months in average. When clinical symptoms is due to the metastasis to a certain organs, proper chemotherapy of radiotherapy might relieve the symptoms and prolong the survival time. When the following symptoms and signs with unknown causes such as enlargemeut of supraclavicular lymph nodes, local ostealgia, horseness, and apyreitc pleural effusion etc were detected in middle-aged and aged patients the doctors should maintain vigilance for the possibility of lung cancer metastasis, further examinations would be necessary. New approuches to the prevention and therapy of metastsis of lung cancer await burther investigation and exploration.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1991年第1期56-58,83,共4页
Chinese Journal of Cancer
关键词
肺肿瘤
诊断
Lung. Bronchogenic Carcinoma
