摘要
目的探讨骨髓培养在儿童侵袭性真菌病中的诊断价值。方法回顾性分析2005年1月至2012年4月进行骨髓培养的29例侵袭性真菌病患儿的临床表现、血液和骨髓培养结果及诊断情况。结果在疑似侵袭性真菌病并进行骨髓培养的62例病例中,29例确诊为侵袭性真菌病,其中骨髓培养阳性14例,阴性48例;血培养阳性5例,阴性57例。骨髓培养和血培养阳性率比较,差异有统计学意义(χ2=4.27,P<0.05)。结论骨髓培养可以较好地指导儿童侵袭性真菌病的诊断。
Objective To study the value of bone marrow culture for the diagnosis of invasive fungal disease （IFD） in children. Methods Twenty-nine hospitalized cases of IFD were studied. The clinical data, including clinical manifestation, blood and bone marrow culture results and diagnosis were retrospectively analyzed. Results The bone marrow culture was positive in 14 patients and negative in 48 patients. However, the blood culture was positive in 5 patients out of the 62 patients. There was a significant difference between bone marrow culture and blood culture. Conclusions Bone marrow culture is a reliable method for the diagnosis of IFD in children. The result of fungal susceptibility test provides valuable information forclinical treatment.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2012年第12期1172-1173,1177,共3页
Journal of Clinical Pediatrics
关键词
骨髓培养
侵袭性真菌病
儿童
bone marrow culture
invasive fungal disease
child
