摘要
缺氧诱导因子1d（HIF—1a）通常在肿瘤中呈现高表达，对肿瘤的生长有促进作用。HIF-1a因子与肿瘤病情、诊断和预后相关。因此，可将HIF-1因子作为肿瘤治疗的重要靶点，从转录、转录后和靶点水平提高治疗效率，延长患者的生命。
Hypoxia inducible factor-1a（ HIF-1a） is usually highly expressed in tumor cells, and can promote tumor growth. HIF-1a is correlated with tumor condition, the diagnosis and the prognosis. Therefore, HIF-1a can be used for tumor treatment in the level of transcription, pro-transcription and target. It is possible to improve the treatment efficiency, and to lengthen patients lifespan.
出处
《国际肿瘤学杂志》
CAS
2012年第12期889-892,共4页
Journal of International Oncology
基金
重庆市自然科学基金资助项目（2010BB5191）
关键词
肿瘤
缺氧诱导因子1
诊断
治疗
Neoplasms
Hypoxia-inducible factor 1
Diagnosis
Therapy
