摘要
心理应激可以造成心理疾病与生理疾病。心理应激通过一系列反应导致内质网应激。内质网应激通过炎症、凋亡等过程导致心身疾病、心理疾病、神经退行性疾病。本文将对内质网应激在心理应激相关疾病中的作用的分子机理做一综述。
The psychological stress could result in psychological diseases and physiological diseases.And the psychological stress could cause endoplasmic reticulum stress by a series of reactions.The endoplasmic reticulum stress play roles in psychophysiological disorders,mental illnesses and neural degeneration diseases by mediating inflammation,apoptosis and the other processes of pathophysiology.This work reviewed some molecular mechanisms on the endoplasmic reticulum stress playing roles in the diseases related with the psychological stress.
出处
《生命的化学》
CAS
CSCD
2012年第6期567-573,共7页
Chemistry of Life
基金
国家自然科学基金项目(81160162)
云南省应用基础研究基金项目(2010CD197)资助
关键词
内质网应激
心理应激
心身疾病
心理疾病
endoplasmic reticulum stress
psychological stress
psychophysiological disorder
mental illness
