摘要
目的探讨沙丁胺醇联合布地奈德雾化吸入疗法治疗支气管哮喘急性发作的临床应用价值及安全性。方法回顾性研究分析本院急诊内科治疗的80例支气管哮喘急性发作患者,随机均分成2组,观察组采用沙丁胺醇和布地奈德雾化吸入疗法联合治疗,对照组采用地塞米松磷酸钠注射液治疗。观察2组治疗前后的总体疗效和肺功能改善指标等。结果观察组在治疗后肺功能恢复情况和外周血的各项指标的改善情况显著优于对照组,且观察组的胸闷气短、肺哮鸣音、咳嗽等主要临床症状的持续时间显著下降。结论沙丁胺醇联合布地奈德雾化吸入疗法治疗支气管哮喘急性发作疗效确切,可快速改善哮喘急性发作症状,增强肺功能,且不良反应少,安全可靠,值得临床推广应用。
Objective To investigate the clinical application and safety of nebulized salbuta- tool combined with bude^nide in the treatment of acute attack of bronchial asthma. Methods Eighty patients with acute attack of bronchial asthma in the Emergency Internal Medicine of our hospital were analyzed retrospectively and were randomly divided into 2 groups, 40 in each group. The observation group received the treatment of salbutamol and budesonide inhalation therapy, and the control group received dexametha^ne sodium phosphate. The overall efficacy and improvement of pulmonary function before and after treatment in two groups were observed. Results The post- operative pulmonary function recovery and various indices of peripheral blood in the observation group were significantly better than those in the control group, and the shortness of breath, pul- monary wheeze, cough and other major clinical symptom duration in the observation group decreased significantly. Conclusion The treatment of nebulized salbutamol combined with budesonide on the acute attack of bronchial asthma has definite curative effect and could improve acute exacerbations of asthma symptoms quickly and speed the recovery of lung function. It has less side effects and is safe and reliable and it is worthy of clinical application.
出处
《实用临床医药杂志》
CAS
2012年第21期110-112,共3页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11220197)