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大分割放疗联合唑来膦酸治疗骨转移癌的疗效观察 被引量:4

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摘要 目的评价大分割放疗联合唑来膦酸治疗骨转移癌的疗效。方法将86例骨转移癌患者分为两组,单纯放疗组48例DT40~50Gy,2~5次/周,3~5Gy/次;联合放疗组38例应用唑来膦酸4 mg静脉滴注,加局部放疗DT40~50Gy,2~5次/周,3~5Gy/次。结果全组病例71例有效,总有效率82.6%。单纯放疗组CR率20.8%,PR率52.1%,总有效率72.9%;联合放疗组CR率30.2%,PR率52.3%,总有效率94.7%.两组比较有统计学差异(P<0.05)。两组比较放疗至疼痛缓解的时间基本相近,疼痛缓解持续时间联合放疗组略高于单纯放疗组,但无统计学差异(P>0.05)。结论大分割放疗联合唑来膦酸治疗骨转移癌的疗效高于单纯放疗,能够较快的缓解患者的疼痛症状,提高患者的生存质量,有可能成为骨转移癌治疗的一种新的标准模式。
出处 《中国医药指南》 2012年第34期515-516,共2页 Guide of China Medicine
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