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重症感染患儿检测血清STNFRs、CRP、IAP的临床意义 被引量:4

The clinic significance of serum STNFRs, CRP and IAP in the children with severe infection
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摘要 目的 :评价可溶性肿瘤坏死因子受体 (STNFRs)、免疫抑制酸性蛋白 (IAP)及C-反应蛋白 (CRP)对重症感染患儿辅助诊断及预后判断的价值。方法 :收集儿科住院急性感染患儿病例 ,分为严重细菌感染组、一般细菌感染组及病毒性脑炎组共 3组 ,分别有 16、 17和 15例 ,于入院时检测以上指标。以正常儿童 19例为对照。结果 :严重细菌感染组各指标均明显升高 (P <0 0 5 )。STNFRⅠ与肾功能及白细胞数相关 ,STNFRⅡ与血液酸碱度相关 ,CRP与白细胞数相关。急性感染患儿预后与入院时STNFRⅠ值相关。结论 :STNFRs、CRP、IAP可作为严重细菌感染患儿的辅助诊断指标 。 To acid pro tein(IAP) and C-reactive protein (CRP) a s a dictation for diagnosing and predict ing the outcome of the children with sev ere infection.Methods:There included thr ee groups,which were the groups of sever e bacterial infection,mild bacterial inf ection and viral encephalitis.There were 16,17 and 15 children in each of the gr oup respectively.The STNFRs,IAP and CRP were measured for those groups,and contr asted with the normal levels.Resul ts:Tho se markers were elevated in severe bacte rial infectious children(P<0 05).STNFRⅠ wa s related with the renal function and th e number of blood white cells.STNFRⅡ was related to the blood pH,and CRP was rel a ted to the number of the blood white cel ls.The outcome of the acute infectious c hildren was correlated with the level of STNFRⅠ in admission.Conclusion:STNFRs,I AP and CRP are useful markers for the d iagnosis of severe bacterial infection o f children,as while serum STNFRⅠ is an e ffective marker for predicting the outco me of the acute infectious children.
出处 《急诊医学》 CSCD 2000年第3期171-172,174,共3页
关键词 儿童 重症感染 血清诊断 STNFRs CRP IAP Soluble tumor necrosis factor receptorsC-reactive proteinImmunosuppressive acid protein
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