摘要
目的:观察T细胞亚群在支原体肺炎中的变化,探讨其在支原体肺炎发病中的作用。方法:采集肺炎支原体患者及对照组肺泡灌洗液(BALF),采用单克隆抗体-碱性磷酸酶法(APAAP)进行T淋巴细胞亚群检测(CD3、CD4、CD8、CD4/CD8)。结果:在55例支原体肺炎患者中,T细胞亚群CD3、CD4降低、CD8增高、CD4/CD8比值降低,与对照组间有显著差异(P<0.05)。结论:免疫功能低下可能在支原体肺炎疾病的发病过程中起到重要作用,支原体肺炎患者的CD3、CD4、CD8、CD4/CD8存在一定的变化规律。
Objective：To observe T lymphocyte subsets in mycoplasma pneumonia changes and discuss its role in the pathogenesis of mycoplasma pneumonia.Methods：Collecting of bronchoalveolar lavage fluid（BALF） in patients with mycoplasma pneumoniae and control groups,using method of monoclonalantibody-alkaline phosphatase（APAAP） to detect T-lymphoc.ytes（CD3,CD4,CD8,CD4/CD8）.Results：In 55 sufferers of mycoplasma＋pneumonia,CD3,CD4 decreased,CD8 increased,CD4/CD8 ratio decreased in T cell subsets,there are significant differences between the patient group and control group（P0.05）.Conclusion：Immunosuppression may play an important role in the pathogenesis of mycoplasma pneumonia disease＇s process,there is some variation in patients with mycoplasma pneumonia of CD3,CD4,CD8,CD4/CD8.
出处
《医学理论与实践》
2012年第23期2866-2867,共2页
The Journal of Medical Theory and Practice
关键词
支原体肺炎
肺泡灌洗液
T细胞亚群
Mycoplasma pneumonia
Bronchoalveolar lavage fluid
T lymphocyte subsets
