摘要
目的:探讨糖化血红蛋白(HbA1c)水平在糖尿病血液透析患者中的变化及意义。方法:2007年1月-2010年1月采用病例回顾性分析的方法,对90例糖尿病血液透析患者,按HbA1c控制标准分成达标组(HbA1c≤6.5%)43例和未达标组(HbA1c>6.5%)47例,比较两组患者的生存率、并发症以及死亡原因。结果:3年后达标组患者生存27例,生存率为62.79%;未达标组患者生存22例,生存率为46.81%;未达标组3年生存率明显低于达标组,其差异具有统计学意义(P<0.05)。未达标组患者因感染死亡12例,占48.00%,心血管疾病死亡6例,占24.00%,脑血管疾病死亡2例,占8.00%,其他5例,占20.00%。结论:糖化血红蛋白未达标组的患者预后较达标组患者差,良好的血糖控制对于DM透析患者是很有价值的。对于糖尿病透析患者,积极控制血糖,可以改善患者的临床症状,提高患者生存率。
Objective：To explore the clinical meaning of glycosylated hemoglobin in diabetic patients who is with hemodialysis therapy.Methods：A retrospective study was done from January 2007 to January 2010,43 diabetes patients with HbA1c≤6.5% were selected as experiment group and 47 diabetes patients were selected with HbA1c6.5% as control group.The cause of death,complications and survival of the two groups of patients were compared.Results：3 years later,there were 27 survivals（62.79%） in the experiment group and there were 22 survivals（46.81%） in the control group.The 3-year survival rate in the control group was lower than that in the experiment group,the difference was statistically significant（P〈0.05）.In the control group,12 cases（48.00%） died of infection;6 cases（24.00%） died of cardiovascular disease;2 cases（8.00%） died of cerebrovascular diseases;5 cases（20.00%） died of other reasons.Conclusion：The curative effect of hemodialysis in HbA1c6.5% group is worse than that in HbA1c≤6.5% group.To diabetic patients with hemodialysis therapy,active sugar control is very important.
出处
《医学理论与实践》
2012年第24期3014-3015,共2页
The Journal of Medical Theory and Practice
关键词
糖尿病
血液透析
糖化血红蛋白
Diabetic
Hemodialysis
Glycosylated hemoglobin
