摘要
目的:探讨金黄色葡萄球菌耐药性及临床防治对策。方法:使用美国BD公司PHOENIX-100全自动细菌鉴定/药敏仪鉴定和药敏。结果:110株金黄色葡萄球菌高产β-内酰胺酶88%,MRSA检出率64.5%;呈低度耐药的抗菌药物有替考拉宁、呋喃妥因、复方新诺明,高度耐药的有青霉素、氨苄青霉素、红霉素等,目前未发现耐万古霉素和利奈唑胺的菌株。结论:金黄色葡萄球菌呈多重、高度耐药性,尚未发现耐万古霉素和利奈唑胺的菌株,因此临床须对该菌做药敏和耐药酶检测,科学合理选择抗菌药物给予治疗。
Objective：To detect the drug resistance of Staphylococcus aureus and clinical control measures. Methods：Staphylococcus aureus were identified and analyzed antimicrobial susceptibility test（AST） by using Phoenix - 100 Automated Microbiology System of BD company. Rusults：The incidence of 110 Strains Staphylococcus aureus producing β -lactamase was 88% , and MRS accounted for 64. 5% of the strains tested. Drug susceptibility results showed that they were lowly resistant to Teicoplanin, Nitrofurantoin,SMZ,and highly resistant to Penicillin, Ampicillin, Erythromycin sodium. All isolates were susceptible to Vancomycin and Linezolid. Conclusion： Staphylococcus aureus show high -ievel multi - drug resistance. All isolates were susceptible to Vancomycin and Linezolid. Antimicrobial Enzyme should be rationally used so as to decrease the prevalence of strains with multi - drug resistance.
关键词
葡萄球菌
药敏
耐药酶
Staphylococcus aureus AST Antimicrobial Enzyme
