摘要
目的比较吗啡术后硬膜外自控镇痛（Ｅ组）与术后病人自控镇痛（Ⅰ组）的效果。方法Ｅ组术后病人１６例，根据患者主观感受每次经由硬膜外腔注药５ｍｌ（布比卡因１５ｍｇ、氟哌啶５ｍｇ、吗啡３ｍｇ，生理盐水稀释至１５ｍｌ），３０ｍｉｎ仍觉疼痛可再追加５ｍｌ，２４ｈ后末次注药镇痛维持在８ｈ以上者可拔管停止镇痛。 Ⅰ组病人 １６例术毕经由静脉ＰＣＩＡ泵持续每小时注入药液０．５ｍｌ（吗啡４０ｍｇ、氟哌啶５ｍｇ生理盐水释至２０ｍｌ），镇痛不满意时可追加１次注入０．５ｍｌ，锁定时间５ｍｉｎ。于术后８、１２、２４ｈ记录吗啡用药量、疼痛程度评分、整体满意度、恶心呕吐副作用等。结果各时点吗啡用药量、疼痛ＶＡＰＳ评分Ⅰ组均明显高于Ｅ组，且两组术后呼吸、平均动脉压均在正常范围。结论 Ｅ组吗啡用量小，镇痛效果明显优于Ⅰ组。
Objective To compare the efficiency, and side effects of morphine for the post-operation patient controlled epidoral analgesia with patient-controlled intravenous morphine. Methods Thirty-two patients un dergoing lowabdome procedures under epidural anesthesia were randomly assigned to the post-operation con trollded epidural analgesia group or patient-controlled intravenous analgesia group. Results The pain relief was better by the post-operative patient-controlled epidural analgesia. Conclusion The dosage of morphine was less than by another way.
出处
《哈尔滨医科大学学报》
CAS
2000年第3期208-209,共2页
Journal of Harbin Medical University
关键词
吗啡
术后止痛
硬膜外腔
morphine
post-operative analgesia
epidural space
