摘要
目的探讨原发性高血压（ＥＨ）患者运动前后血压、心率的变化，以及心功能和房促尿钠多肽（ＡＮＰ）变化的相互关系及临床意义。方法１２１例ＥＨ患者和４１例血压正常值者进行组间血压心率比较和用多元线性回归分析法评价两组运动前后心功能与ＡＮＰ之间的相互关系。结果运动可使ＥＨ患者心功能得到一定改善，血清ＡＮＰ含量可反应心脏舒张功能储备损害和左心室顺应性损害的程度。结论 ＥＨ患者适当运动有益于降低血压和改善心功能。
Objective To explore clinical significance and relationship of blood pressure (BP) and heart rate (HR) as well as heart function (HF) and atrial natriuretic peptide (ANP) between patients with essential hypertension (EH) and control persons after and before exercise. Methods To evaluate relationship between HF and ANP with multi line regression method and to compare HR and BP between 121 patients with EH and 41 control persons after and before exercise. Results HF of patients with EH could be improved by exercise. Serum concentration of ANP could reflect the damage degree of heart diastolic function restore and left ventricle acclimation. Conclusion It is beneficial to exercise suitably for decreasing blood pressure and improving heart function of patients with EH.
出处
《哈尔滨医科大学学报》
CAS
2000年第3期193-195,共3页
Journal of Harbin Medical University
关键词
原发性高血压
心功能
房促尿钠多肽
essential hypertension
heart function
atrial natriuretic peptide
