摘要
目的了解中国汉族人群 α1 -抗糜蛋白酶表型的分布情况。方法建立测定 α1 -抗糜蛋白酶表型的聚丙烯酰胺凝胶等电聚焦免疫固定技术并应用这种方法对居住在重庆市汉族群体的 2 0 0例个体的 α1 -抗糜蛋白酶表型进行分析。结果发现中国汉族人群 α1 -抗糜蛋白酶具有 3种表型。结论据此推测 α1 -抗糜蛋白酶有希望成为人类遗传学新的遗传标记 ,同时为进一步开展α1 -抗糜蛋白酶遗传多态性与疾病的相互关系研究拓宽了视野。
ObjectiveTo understand distribution of phenotypes of α 1 antichymotrypsin (α 1 ACT) in a Han Population in China MethodsPhenotypes of α 1 ACT have been determined by isoelectric focusing on the polyacrylamide gel followed by immunofixation The phenotype frequencies of α 1 ACT were investigated using this method in the Han Population in Chongqing ResultsThree phenotypes of α 1 ACT were found in the Han Population in Chongqing ConclusionsThis study provide clues for α 1 ACT to be a new and promising genetic marker and build a basis of related study between genetic polymorphism of α 1 ACT and diseases [
出处
《免疫学杂志》
CAS
CSCD
北大核心
2000年第4期287-288,共2页
Immunological Journal
基金
国家自然科学基金!资助项目 395 70 749
