摘要
目的:分析上海市浦东新区2004年恶性肿瘤患者生存情况,为制订肿瘤防治策略提供参考依据。方法:采用上海市肿瘤病例登记报告系统,收集浦东新区各地区2004年诊断为恶性肿瘤的8 907例患者信息,采用寿命表法计算观察生存率(OSR),Ede-rⅡ法计算相对生存率(RSR)。结果:浦东新区2004年共登记恶性肿瘤发病8 907例,发病率为357.51/10万;恶性肿瘤患者1～5年OSR分别为45.30%、39.74%、36.62%、34.14%和32.41%;1～5年RSR分别为48.44%、44.08%、42.78%、42.51%和41.64%;其中结直肠癌、甲状腺癌、膀胱癌、乳腺癌和脑中枢神经系统肿瘤的5年RSR>40%;胰腺癌和肝癌的5年RSR<10%;不同性别、年龄、地区和病理分期的恶性肿瘤患者总生存率的差异有统计学意义,χ2值分别为352.298、1 472.077、33.913和1 052.113,P值均<0.01;1、3和5年RSR随发病年龄的增加而有降低的趋势,差异有统计学意义,t值分别为-51.450、-56.551和-73.479,P值均<0.01。结论:浦东新区部分人群恶性肿瘤生存率较低,主要影响因素为肿瘤类别、性别、年龄、地理分布和病理分期。
OBJECTIVE： To analyze the survival rates of cancer patients in 2004 in Pudong new area and provide data for cancer prevention project. METHODS： Subsets of 8 907 cancer patients diagnosed in 2004 in Pudong new area were selected by the Cancer Reporting System in Shanghai. The observed survival rates for different groups of gender, age, geographical distribution and TNM stages were calculated and tested by Life Table and log-rank test. Relative survival rate was calculated using Ederer Ⅱ method. RESULTS： The incidence rate of cancers in Pudong new area in 2004 was 35.75 per million. The observed survival rate of the cancer cases at one to five years was 45.30% ,39.74% ,36.62% ,34.14% and 32.41% ,and the relative survival rate （RSR） was 48.44%, 44.08 %, 42.78%, 42.51 % and 41.64%, respectively. The cancers with a 5-year RSR of more than 40 % were colorectal, breast, thyroid, brain and central nervous system and bladder cancers,and the cancers with a 5-year RSR of less than 10% were liver and pancreas cancers. The difference showed statistical significance （χ^2 values were 352. 298,1 472. 077,33. 913 and 1 052. l13,P〈0.01） among the different groups ＇ overall survival in gender, age, district and TNM stages respectively. The RSR of 1-, 3- and 5-year were decreased with the increased age of incidence （t values were -51. 450,-56. 551 and -73. 479, P〈0.01 ）. CONCLUSIONS： The survival rate is low for some cancer patients in Pudong new area. The factors affecting the cancer survival are tumor types, gender,age,geographical location and TNM stages of the cancer patients.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2012年第21期1614-1619,共6页
Chinese Journal of Cancer Prevention and Treatment
基金
浦东新区卫生系统重点学科建设基金(PWZxk2010-09)
关键词
肿瘤
预后
预后分析
统计学
上海
neoplasms
prognosis
factor analysis, statistical
SHANGHAI
