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炎症反应及抗炎药物与阿尔茨海默病的研究进展 被引量：17

Recent advance in inflammatory reaction and anti-inflammatory drugs in Alzheimer＇s disease
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摘要 阿尔茨海默病（Alzheimer＇s disease,AD）又称老年性痴呆，是一种常见的以认知功能进行性减退为特征的中枢神经系统（CNS）变性疾病，其病因和发病机制十分复杂．迄今仍未完全阐明。近年来越来越多的实验和临床证据表明．AD、帕金森病和多发性硬化等CNS疾病均与炎症反应有关．而对AD的研究表明：大量已知的炎症因子参与了AD的炎症损伤病理过程，在老年斑周围有大量活化的胶质细胞和炎症细胞，
作者 官杰 李浩 刘剑刚
机构地区 青岛市海慈医疗集团内分泌科 中国中医科学院西苑医院老年病科 中国中医科学院西苑医院心血管病中心科
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2012年第12期1282-1285,共4页 Chinese Journal of Neuromedicine
基金 国家自然科学基金（30873338） 国家科技重大专项课题（2009ZX09103-391）
关键词 阿尔茨海默病 炎症反应 抗炎药物 Alzheimer＇s disease Inflammation Anti-inflammatory agent
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献32

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二级参考文献27

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二级引证文献101

中华神经医学杂志
2012年 第12期

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