摘要
目的 :观察地尔硫对轻、中度原发性高血压 (EH)患者生活质量的影响。方法 :应用单盲法 ,通过生活质量调查表调查 12 8例轻、中度 EH患者用药前后存在躯体症状、健康愉快感、工作表现、抑郁水平、生活满意度、业余活动及认知功能等方面的情况。结果 :患者在躯体症状、健康愉快感、工作表现、认知功能等方面均有明显改善 (P <0 .0 5～ 0 .0 1) ,而对抑郁水平、业余活动及生活满意度等方面无明显影响。结论 :地尔硫可明显改善轻、中度 EH患者的生活质量。
Objective:A single blind clinical trial was conducted in 128 patients with mild to moderate hypertension to observe the effect of diltiazem on life quality.Method:An assessing table was used to investigate the status of physical symptoms, sense of well being,work performance, scores of depression, satisfaction with life, leisure activity and cognitive function before and after diltiazem administration.Result:After a 6 month treatment,the physical symptoms, sense of well being, work performance and cognitive function were improved significantly(P< 0.05 ~ 0.01 ),meanwhile, the drug had no significant effects on the scores of depression, leisure activity and satisfaction with life.Conclusion:Diltiazem may improve the quality of life of the patients with mild to moderate hypertension.
出处
《临床心血管病杂志》
CSCD
北大核心
2000年第6期266-267,共2页
Journal of Clinical Cardiology
