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地塞米松延长骨科手术中布比卡因硬膜外麻醉及术后镇痛的时效 被引量:5

A RANDOMIZED DOUBLE-BLIND COMPARISION OF EPIDURAL ANESTHESIA WITH DEXAMETHASONE AND BUPIVACAINE MIXTURE VERSUS BUPIVACAINE FOR ORTHOPEDIC SURGERY AND POSTOPERATIVE ANALGESIA
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摘要 目的 :观察地塞米松对布比卡因硬膜外麻醉效果的影响。方法 :选择中等骨科手术患者 ,随机分为两组 ,A组采用 0 .75 %布比卡因 10ml+1%利多因卡因 2 0 0mg硬膜外麻醉 ;B组采用 0 .75 %布比卡因 10ml+1%利多卡因 2 0 0mg +地塞米松 10mg硬膜外麻醉 ,观察麻醉起效时间和术后镇痛时间。结果 :A、B两组麻醉起效时间和术后镇痛时间存在显著差异。结论 :采用地塞米松和布比卡因硬膜外麻醉镇痛起效快 ,镇痛效果可靠 ,副作用小 ,是一种良好的麻醉镇痛方法。 Aim: To evaluate the effect of epidural anesthesia and postoperative analgesia with dexamethasone and bupivacaine. Methods: 100 lower limb fracture patients were randomly distributed to two groups and adminitered with two different solutions in a blind manner. Solution A: bupivacaine 0.75% 10ml+lidocaine 1% 200mg. Solution B: 0.75% 10ml+lidocaine 1% 200mg+dexamethasone 10mg. The patients were observed for the starting time of anesthesia as well as the duration of anesthesia, and the lasting period of post operative analgesia. Results: There were obvious difference between the two groups in the starting time of anesthesia and the duration of post operative analgesia. Conclution: Bupivacaine in combination with dexamethasone for epidural anesthesia produced a rapid onset, longer lasting post operative analgesia with fewer aversive side effects.
出处 《中国疼痛医学杂志》 CAS CSCD 2000年第2期83-84,共2页 Chinese Journal of Pain Medicine
关键词 地塞米松 布比卡因 硬膜外麻醉 骨科手术 镇痛 Dexamethasone Bupivacaine Epidural anesthesia
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  • 1张元信,中华医学杂志,1998年,78卷,164页
  • 2张元信,中国临床药理学杂志,1997年,2卷,196页
  • 3王英伟,国外医学.麻醉学与复苏分册,1995年,13卷,318页
  • 4张善桂,国外医学.麻醉学与复苏分册,1992年,13卷,318页
  • 5刘俊杰,现代麻醉学,1991年,213页
  • 6团体著者,药理学,1980年,276页

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