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超声检查视神经鞘直径在颅脑损伤诊治中的应用价值 被引量:4

Study on the clinic application value of ultrasonography examination of optic nerve sheath diameter in brain inury
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摘要 目的探讨超声检查视神经鞘直径(OpticNerveSheathDiameter,ONSD)在颅脑损伤诊治中的应用价值。方法选择2008年7月至2011年6月本院颅脑损伤患者90例为观察组,其中入院时GCS评分为轻、中、重型颅脑损伤患者各30例,依次分为A、B、c三组;另招募本院正常体检者50例及神经外科门诊志愿者50例为对照组D组。入院后1、3、7、14d用彩超经眼眶检查观察组、对照组眼球后3mm处ONSD大小,每眼检查3次,计算全部受检者ONSD平均值,标准差;彩超检查后0.5h腰穿测不同组别颅内压,计算其平均值,对所有数据进行统计分析。结果入院后1、3、7、14d,A组ONSD分别为(4.54±0.32)mm、(4.42±0.30)mm、(4.44±0.32)mm、(4.43±0.25)mm;B组ONSD分别为(4.48±0.28)mm、(4.52±0.24)mm、(4.46±0.28)mm、(4.38±0.22)mm;C组ONSD分别为(5.67±0.35)mm、(6.36±0.42)mm、(5.65±0.23)mm、(4.76±0.35)mm。入院后1、3、7、14d,A组颅内压分别是(82±11)mmH20、(79±12)mmH20、(90±15)mmH20、(86±14)mmH20;B组颅内压分别是(78±15)mmH20、(85±10)mmH20、(78±16)mmH:0、(80±11)mmH20;C组颅内压分别是(225±26)mmH20、(288±23)mmH20、(256±23)mmH20、(122±18)mmH20;D组ONSD值(4.58±0.41)mm,颅内压值(88±10)mraH20。A与B、A与D、B与D之间比较差异无统计学意义(P〉0.05);A与c、B与c、D与c之间比较差异有统计学意义(t=12.24~24.67,P〈0.01)。结论轻、中型颅脑损伤患者ONSD及颅内压无明显变化;重型颅脑损伤患者伤后不同时间颅内压变化不同,ONSD随颅内压的升高而增大,超声检查ONSD在颅脑损伤诊治中具有重要价值,能反应颅内压的升高,是一种非侵袭、操作方便、快速易行的颅高压评估方法。 Objective To explore the clinic application value of ultrasonography examination of op tic nerve sheath diameter(ONSD) in brain injury. Methods From July 2008June 2011,90 cases of brain injured patients were chosen as experimental group including light ( A group ), medium ( B group ), and heavy (C group) brain injured patients according to the admission GCS score ;50 cases of conventional phys ical examination and 90 cases of volunteers 50 in neurosurgical outpatient were chosen as control group. The ONSD of both groups were measured 3 mm behind the globe through orbital using color sonographic with dif ferent time after admission. 3 times measurements were carried out for every optic nerve sheath. All clientONSD mean and standard deviation were calculated. In 0. 5 h after color dopplar ultrasound examination, lumbar vertebra puncturing measured intracranial pressure in different groups. Results After admission (1 d, 3 d, 7 d, 14 d), the ONSD of A group was (4. 54 ±0. 32) mm, (4. 42 ± 0. 30) mm, (4. 44 ± 0. 32) m, and ( 4. 43 ± 0. 25 ) mm, re speetively; The ONSD of B groups was (4. 48± 0. 28 ) mm, (4. 52 ± 0. 24) ram, (4. 46 ±0. 28)mm, and (4. 38 ±0. 22)mm, respectively; The ONSD of C group was (5, 67 ±0. 35)mm, (6. 36 ± 0.42 ) mm, ( 5.65±0.23 ) mm, and (4. 76 + 0. 35 ) mm, respectively. After admission ( 1 d, 3 d, 7 d, 14 d), the intraeranial pressure (IP) of A group was ( 82 ± 11 ) mmH2 O, ( 79 ± 12 ) mmH2 O, (90 ± 15)mmH20, and (86 ± 14)mmH20, respectively; The IP of B group was (78 ± 15)mmH20, (85 ± 10) mmH2 O, (78 ±16) mmH2 O, ( 80 ±11 ) mmH2 O, The IP of C group was (225 ± 26) mmH2 O, (288± 23 ) mmH2 O, ( 256 ± 23 ) mmH2 O, ( 122 ± 18 ) mmH2 O, respectively. Group D had the ONSD average of (4. 58 ± 0. 41 )mm and IP of (88 ±0.41 )mmH20 after eyeball 3mm place. No differenee was found between A and B, A and D, or B and D ( P 〉 0.05) ; A difference was found between A and C, B and C, or D and C ( t = 12. 24 24. 67, P 〈 0. 01 ). Conclusions The ONSD and IP in light medium brain injured patients had no change. In patients with severe brain injury, IP changed with the time after injury, the ONSD in creased with the IP, the ultrasonography examination of ONSD with the important value in the diagnosis and treatment can respond the IP increase, which is a noninvasion, convenient, fast, and feasible method for e valuation of cranial high pressure.
出处 《中国医师杂志》 CAS 2012年第11期1459-1462,共4页 Journal of Chinese Physician
基金 广东省社会发展领域科技计划项目(93101) 深圳市科技计划项目(200903226)
关键词 神经鞘 超声检查 视神经 颅脑损伤 诊断 颅脑损伤 治疗 Neurilemma/ultrasonography Optic nerve Craniocerebral trauma/diagnosis Cranio-cerebral trauma/therapy
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参考文献11

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二级参考文献10

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  • 2Malayeri AA,Bavarian S,Mehdizadeh M. Sonographic evaluation of optic nerve diameter in children with raised intracranial pressure[J].Journal of Ultrasound in Medicine,2005,(02):143-147.
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共引文献10

同被引文献32

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  • 7Beare NA, Kampondeni S, Glover S J, et al. Detection of raised in- tracranial pressure by ultrasound measurement of optic nerve sheath diameter in African children [J]. Trop Med Int Healt, 2008, 13(11): 1400-1404.
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  • 10Tayal VS, Neulander M, Norton HJ, et al. Emergency department so- nographhic measurement of optic nerve sheath diameter to detect findings of increased intraeranial pressure in adult heat injury pa- tients [J']. Ann Emerg Med, 2007, 49(4): 508-514.

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二级引证文献38

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