摘要
【摘要】目的探讨全身运动对乳腺癌患者生活质量、疲乏感、抑郁感、焦虑感和体象的影响。方法通过计算机检索Cochrane图书馆、Pubmed、EMBASE、CINAHL、Psycinfo、SportDiscus、中文期刊全文数据库和中国生物医学文献数据库2002年至2011年10年间的英文和中文文献资料。要求文献内容为针对乳腺癌患者进行运动干预的独立随机对照研究（RCT），严格对文献质量进行评价，并提取相关结局指标进行Meta分析。结果最终纳入文献16篇，其中英文13篇，中文3篇。分别有4篇、6篇、9篇、5篇、3篇、4篇文献纳入对FACT-B总分、FACT—B乳腺癌分量表、疲乏感、抑郁感、焦虑感、体象的Meta分析。结果显示，经过全身运动，干预组FACT—B总分和乳腺癌分量表得分显著高于对照组，疲乏感、抑郁感和焦虑感明显减轻，自尊增强。对各结局指标进行发表偏倚分析，结果显示均无发表偏倚存在。对各结局指标进行敏感性分析，结果与原分析结果相比无明显变化。结论全身运动对乳腺癌患者生活质量的改善以及相关心理社会问题的缓解都起到了积极的作用。可将运动锻炼融人患者的日常生活，以进一步达到促进患者康复的目的。
Objective To evaluate the effect of physical exercise on health-related quality of life （HRQol）, fatigue, depression, anxiety and body- image in breast cancer patients. Methods The Cochrane Library, Pubmed, EMBASE, CINAHL, Psyeinfo, SportDiscus, CNKI and CBMdise were searched to collect randomized controlled trials （RCTs） from 2002 to 2011 which mentioned the physical exercise to breast cancer patients. The quality of the RCTs was appraised and the data were extracted. Results In total, 16 RCTs were included. Statistically significant results were found for the effect of physical exercise on HRQol, fatigue, depression, anxiety and body- image. The presence of publication bias was explored and no publication bias was detected. Sensitivity analysis were also performed and there were no significant dif- ferences with the former resuhs. Conclusions The results indicated that physical exercise improve HRQol and psychological outcomes in breast cancer patients. Breast cancer patients should be taught to do some moderate exercises as part of their lives to promote rehabilitation.
出处
《中国实用护理杂志》
北大核心
2012年第36期58-62,共5页
Chinese Journal of Practical Nursing
基金
南京中医药大学哲学社会科学基金项目（11XSK11）
关键词
乳腺癌
运动
生活质量
心理指标
Breast cancer
Physical exercise
Quality of life
Psychological outcomes
