摘要
目的:研究小鼠脑细胞色素C氧化酶(Cytochrome C oxidase,CCO)活性、线粒体细胞色素C(Cytochrome C,Cyt C)含量与年龄的关系,为法医学年龄推断提供新的思路。方法:利用紫外分光光度法检测了1、3、6、9、12月龄昆明小鼠的脑组织CCO活性及线粒体Cyt C含量。结果:小鼠脑组织CCO活性、线粒体Cyt C含量,随着年龄增大而逐渐降低。结论:脑组织CCO活性及线粒体Cyt C含量有望用于年龄推断。
Objective：To provide new ideas for forensic age estimation by studying relationship among cytochrome C oxidase（CCO） activity,contents of cytochrome C（Cyt C）in mitochondria of brain tissues and mice age.Methods：CCO activity and contents of Cyt C in mitochondria of brain tissues of 1,3,6,9,12 months old Kunming mice were detected using UV spectrophotometry.Results：CCO activity and contents of Cyt C in mitochondria of brain tissues were decreased gradually with the increase of mice age.Conclusion： CCO activity and contents of Cyt C in mitochondria of brain tissues may be used for age estimation.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2012年第12期1041-1044,共4页
Journal of Chongqing Medical University
