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Bmi-1基因在甲状腺乳头状中的表达及临床意义 被引量：1

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摘要 目的:探讨Bmi-1基因在甲状腺乳头状癌组织中的表达。方法:收集武汉大学人民医院2000～2006年手术切除及活检的甲状腺乳头状癌标本40例和甲状腺腺瘤标本20例。采用免疫组织化学方法检测甲状腺乳头状癌和甲状腺腺瘤组组织内Bmi-1基因的表达。采用HPIAS-2000图像分析系统测定Bmi-1基因在甲状腺乳头状癌及甲状腺腺瘤中表达的平均光密度和平均阳性面积率。结果:甲状腺乳头状癌组织中Bm i-1基因呈高表达;甲状腺腺瘤中Bm i-1基因呈低表达。结论:Bm i-1基因在甲状腺乳头状癌组织中的高表达,提示Bm i-1基因可能参与了甲状腺乳头状癌的发生和发展。
作者 陈敏
机构地区 江夏区第一人民医院
出处 《数理医药学杂志》 2012年第6期726-727,共2页 Journal of Mathematical Medicine
关键词 甲状腺乳头状癌 BMI-1基因 统计分析
分类号 R735.7 [医药卫生—肿瘤]
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参考文献10

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同被引文献22

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数理医药学杂志
2012年 第6期

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